Scientists working with Modernising Medical Microbiology have developed a new computer program to help keep antibiotics effective. The program: Mykrobe Predictor , can run on a laptop, and in a few minutes can analyse bacterial DNA from a patient’s infection and predict which antibiotics will work. They have released the software to download free at: http://www.mykrobe.com The software is being evaluated by Modernising Medical Microbiology researchers in Brighton, Leeds and Oxford, to see in three UK hospitals to see whether it could help speed up diagnosis of drug-resistant infections and enable doctors to better target the prescription of antibiotics. The software, developed by Phelim Bradley, Dr Zamin Iqbal and colleagues at the Wellcome Trust Centre for Human Genetics, [...]
My name is Luke Anson and I’m a research assistant in the Modernising Medical Microbiology consortium. My job is constantly changing but right now I’m working on new ways to find out how to diagnose and treat blood infections. We’re trying a totally new technique, which involves getting the DNA out of the bacteria that are infecting the blood of patients in the John Radcliffe hospital here in Oxford (Bacteria have DNA, just like humans). This can be really hard work as I have to deal with chemicals that cause problems; Human DNA from the blood cells can also get mixed up with everything. If it’s so hard then you may be wondering [...]
Tuberculosis: MMM is helping the UK lead the world in getting new DNA technologies ready for patient care
Our scientists have led an international team to show we can diagnose patients faster, cheaper and more effectively by analysing the DNA of the bacteria infecting patients. DNA analysis technology has been evolving rapidly over the last 20 years, but this is the first time the technique has been used on such a large scale, in a busy, real-life setting. Researchers all over the world went head-to-head with the ‘traditional’ methods. They showed that DNA analysis was able to detect Tuberculosis and predict which antibiotics should be used up to eight times faster, so patients could receive the right treatment sooner. They were also able to detect and respond to potential outbreaks more rapidly [...]
MMM recently won the Academy of Medical Sciences 'My Team Science' Competition! In this competition, groups were charged with creating an image which showed how they collaborated in Scientific Research. Clickk on the image to see how we work together to perform the DNA Analysis of Tuberculosis bacteria A high quality .pdf can be downloaded here The story behind the story The Team MMM Story represents just a small part of the huge amount of work that goes on, and the many, many different people who contribute to what we do. We have strived for scientific accuracy where possible, (though admittedly DNA doesn't always turn out pink). Whilst we have nominated particular groups for [...]
Professor Derrick Crook has been appointed Director of the National Infection Service of Public Health England (PHE) In his new role, as well as leading Modernising Medical Microbiology Research, he will lead and direct the specialist reference and diagnostic microbiology health protection services provided by Public Health England, and advise PHE’s executive on strategy and policy for microbiology services. Read more here.