April 2012 – March 2013

Insights from genomics into bacterial pathogen populations. Wilson DJ [2012 Sep;8(9):e1002874]

Renal impairment and clinical outcomes of Clostridium difficile infection in two randomized trials. Mullane KM, Cornely OA, Crook DW, Golan Y, Louie TJ, Miller MA, Josephson MA, Gorbach SL. American journal of nephrology. [2013;38(1):1-11]

A modified RNA-Seq approach for whole genome sequencing of RNA viruses from faecal and blood samples. Batty EM, Wong TH, Trebes A, Argoud K, Attar M, Buck D, Ip CL, Golubchik T, Cule M, Bowden R, Manganis C, Klenerman P, Barnes E, Walker AS, Wyllie DH, Wilson DJ, Dingle KE, Peto TE, Crook DW, Piazza P. PloS one. [2013;8(6):e66129]

Short-term genome stability of serial Clostridium difficile ribotype 027 isolates in an experimental gut model and recurrent human disease. Eyre DW, Walker AS, Freeman J, Baines SD, Fawley WN, Chilton CH, Griffiths D, Vaughan A, Crook DW, Peto TE, Wilcox MH. PloS one. [2013;8(5):e63540]

Within-host evolution of Staphylococcus aureus during asymptomatic carriage. Golubchik T, Batty EM, Miller RR, Farr H, Young BC, Larner-Svensson H, Fung R, Godwin H, Knox K, Votintseva A, Everitt RG, Street T, Cule M, Ip CL, Didelot X, Peto TE, Harding RM, Wilson DJ, Crook DW, Bowden R. PloS one. [2013;8(5):e61319]

Effect of age on treatment outcomes in Clostridium difficile infection. Louie TJ, Miller MA, Crook DW, Lentnek A, Bernard L, High KP, Shue YK, Gorbach SL. Journal of the American Geriatrics Society. [2013 Feb;61(2):222-30]

Microevolutionary analysis of Clostridium difficile genomes to investigate transmission. Didelot X, Eyre DW, Cule M, Ip CL, Ansari MA, Griffiths D, Vaughan A, O'Connor L, Golubchik T, Batty EM, Piazza P, Wilson DJ, Bowden R, Donnelly PJ, Dingle KE, Wilcox M, Walker AS, Crook DW, A Peto TE, Harding RM. Genome biology. [2012 Dec 21;13(12):R118]

Secular trends in nosocomial bloodstream infections: antibiotic-resistant bacteria increase the total burden of infection. Ammerlaan HS, Harbarth S, Buiting AG, Crook DW, Fitzpatrick F, Hanberger H, Herwaldt LA, van Keulen PH, Kluytmans JA, Kola A, Kuchenbecker RS, Lingaas E, Meessen N, Morris-Downes MM, Pottinger JM, Rohner P, dos Santos RP, Seifert H, Wisplinghoff H, Ziesing S, Walker AS, Bonten MJ. Clinical infectious diseases : an official publication of the Infectious Diseases Society of America. [2013 Mar;56(6):798-805]

Recombinational switching of the Clostridium difficile S-layer and a novel glycosylation gene cluster revealed by large-scale whole-genome sequencing. Dingle KE, Didelot X, Ansari MA, Eyre DW, Vaughan A, Griffiths D, Ip CL, Batty EM, Golubchik T, Bowden R, Jolley KA, Hood DW, Fawley WN, Walker AS, Peto TE, Wilcox MH, Crook DW. The Journal of infectious diseases. [2013 Feb 15;207(4):675-86]

Whole genome sequencing in the prevention and control of Staphylococcus aureus infection. Price JR, Didelot X, Crook DW, Llewelyn MJ, Paul J. The Journal of hospital infection. [2013 Jan;83(1):14-21]

Whole-genome sequencing to delineate Mycobacterium tuberculosis outbreaks: a retrospective observational study. Walker TM, Ip CL, Harrell RH, Evans JT, Kapatai G, Dedicoat MJ, Eyre DW, Wilson DJ, Hawkey PM, Crook DW, Parkhill J, Harris D, Walker AS, Bowden R, Monk P, Smith EG, Peto TE. The Lancet infectious diseases. [2013 Feb;13(2):137-46]

Fidaxomicin versus vancomycin for Clostridium difficile infection: meta-analysis of pivotal randomized controlled trials. Crook DW, Walker AS, Kean Y, Weiss K, Cornely OA, Miller MA, Esposito R, Louie TJ, Stoesser NE, Young BC, Angus BJ, Gorbach SL, Peto TE, Study 003/004 Teams. Clinical infectious diseases : an official publication of the Infectious Diseases Society of America. [2012 Aug;55 Suppl 2:S93-103]

Predictors of first recurrence of Clostridium difficile infection: implications for initial management. Eyre DW, Walker AS, Wyllie D, Dingle KE, Griffiths D, Finney J, O'Connor L, Vaughan A, Crook DW, Wilcox MH, Peto TE, Infections in Oxfordshire Research Database. Clinical infectious diseases : an official publication of the Infectious Diseases Society of America. [2012 Aug;55 Suppl 2:S77-87]

Transforming clinical microbiology with bacterial genome sequencing. Didelot X, Bowden R, Wilson DJ, Peto TE, Crook DW. Nature reviews. Genetics. [2012 Sep;13(9):601-12]