2012

Eyre DW, Walker AS, Griffiths D, Wilcox MH, Wyllie DH, Dingle KE, Crook DW, Peto TEA. Clostridium difficile mixed infection and re-infection. J Clin Micro 2012; 50(1):142-4. doi: 10.1128/JCM.05177-11. [PMID:22075589]

Golubchik T, Brueggemann AB, Street T, Gertz RE Jr, Spencer CC, Ho T, Giannoulatou E, Link-Gelles R, Harding RM, Beall B, Peto TE, Moore MR, Donnelly P, Crook DW, Bowden R. Pneumococcal genome sequencing tracks a vaccine escape variant formed through a multi-fragment recombination event. Nat Genet 2012 Jan 29;44(3):352-5. doi: 10.1038/ng.1072. [PMID:22286217]

Walker AS*, Eyre DW*, Wyllie DH, Dingle KE, Harding RM, O’Connor L, Griffiths D, Vaughan A, Finney J, Wilcox MH, Crook DW, Peto TEA on behalf of the Infections in Oxfordshire Research Database (IORD). Characterisation of Clostridium difficile hospital ward-based transmission using extensive epidemiological data and molecular typing. Plos Med 2012; 9(2): e1001172. doi:10.1371/journal.pmed.1001172. [PMID: 22346738; PMCID: PMC3274560]

Young BC, Golubchik T, Batty EM, Fung R, Larner-Svensson H, Votintseva AA, Miller RR, Godwin H, Knox K, Everitt RG, Iqbal Z, Rimmer AJ, Cule M, Ip CL, Didelot X, Harding RM, Donnelly P, Peto TE, Crook DW, Bowden R, Wilson DJ. Evolutionary dynamics of Staphylcoccus aureus during progression from carriage to disease. Proc Natl Acad Sci U S A. 2012;109(12):4550-5. [PMID: 22393007]

Schlackow I, Stoesser N, Walker AS, Crook DW, Peto TEA, Wyllie DH. Increasing incidence of E. coli bacteraemia is driven by an increase in antibiotic-resistant isolates: Electronic database study in Oxfordshire 1999-2011. J Antimicrob Chemo 2012; 67(6):1514-24. doi: 10.1093/jac/dks082. [PMID:22438437]

Eyre D*, Golubchik T*, Gordon NC*, Bowden R*, Piazza P, Batty E, Ip C, Wilson D, Didelot X, O’Connor L, Lay R, Buck D, Kearns A, Shaw A, Paul J, Wilcox MH, Donnelly P, Peto TEA*, Walker AS*, Crook DW*. A pilot study of rapid benchtop sequencing of Staphylococcus aureus and Clostridium difficile for outbreak detection and surveillance. BMJ open 2012;2:e001124. doi:10. 1136/bmjopen-2012-001124. [PMID: 22674929]

Eyre DW, Walker AS, Wyllie D, Dingle KE, Griffiths D, Finney J, O’Connor L, Vaughan A, Crook DW, Wilcox MH, Peto TEA on behalf of the Infections in Oxfordshire Research Database (IORD). Predictors of recurrent C. difficile infection: implications for initial management. Clin Inf Dis 2012;55:S77-S87. doi: 10.1093/cid/cis356. [PMID:22752869]

Crook DW, Walker AS, Kean Y, Weiss K, Cornely OA, Miller M, Esposito R, Louie TJ, Stoesser NE, Young BC, Angus BJ, Gorbach S, Peto TEA on behalf of the Study 003/004 teams. Fidaxomicin versus vancomycin for Clostridium difficile infection: meta-analysis of pivotal randomized controlled trials. Clin Inf Dis 2012; 55:S93-S103. doi: 10.1093/cid/cis499. [PMID:22752871]

Schlackow I, Walker AS, Crook DW, Peto TEA, Wyllie DH. Surveillance of infection severity: A registry study of laboratory diagnosed Clostridium difficile. PLoS Med 2012; 9(7): e1001279. doi:10.1371/journal.pmed.1001279. [PMID:22859914]

Didelot X, Bowden R, Wilson DJ, Peto TE, Crook DW. Transforming clinical microbiology with bacterial genome sequencing. Nat Rev Genet 2012; 13(9):601-12. doi: 10.1038/nrg3226. [PMID: 22868263]

Cody AJ, McCarthy NM, Wimalarathna HL, Colles FM, Clark L, Bowler ICJW, Maiden MCJ, Dingle KE. A longitundinal 6-year study on the molecular epidemiology of clinical Campylobacter isolates in Oxfordshire, United Kingdom. J Clin Micro 2012 Oct: 50(10): PMC3457434. doi: 10.1128/JCM.01086-12 [PMID: 22814466 PMCID: PMC3457434]

Wilson DJ. Insights from genomics into bacterial pathogen populations. Plos Path 2012; 8(9):e1002874. doi: 10.1371/journal.ppat.1002874 [PMID: 22969423]

Young BC, Wilson DJ. On the evolution of virulence during Staphylococcus aureus nasal carriage. Virulence 2012; 3(5):454-456. [PMID: 23076245]

Didelot X, Eyre DW, Cule M, Ip CLC, Ansari MA, Griffiths D, Vaughan A, O’Connor L, Golubchik T, Batty EM, Piazza P, Wilson DJ, Bowden R, Donnelly PJ, Dingle KE, Wilcox M, Walker AS, Crook DW, Peto TEA*, Harding RM*. Microevolutionary analysis of Clostridium difficile genomes to investigate transmission. Genome Biology 2012;13(12):R118. [PMID: 23259504]